• Use Cases

How Synthetic Data Boosts Adaptation of AI in Medical Image Analysis

By: SKY ENGINE AI
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Introduction

Uses of artificial intelligence in medicine

Uses of artificial intelligence (AI) are countless, but one of the most intriguing and promising is healthcare. Its possible uses in medicine include among others:

  • diagnostics (e.g., identifying tumors in radiology images), 
  • predictive analytics (e.g., forecasting patient deterioration), 
  • personalized treatment plans (e.g., tailoring cancer therapies based on genetic profiles),
  • patient monitoring (e.g., detecting arrhythmias from ECG data), 
  • operational efficiency (e.g., optimizing hospital resource allocation). 

These applications of artificial intelligence have a potential to permanently transform medicine by empowering healthcare providers with tools for more efficient and personalized care. Moreover, AI applications extend beyond hospitals to remote monitoring and telemedicine, addressing critical challenges in accessibility and scalability while driving innovation across the medical field.

Synthetic data created with SKY ENGINE AI’s platform is grounded in naturally occurring physiology, through the adoption of physical modeling, which consists of two components:

  • a digital model representing a patient, and organ, or a patient population,
  • a digital model of the image acquisition device. 

Unlike the statistical generative models, physically-based models eliminate the risk of hallucinations and unrealistic anatomy, which is crucial especially in the medical uses.  

Computer vision AI in dermatology 

SKY ENGINE AI’s Synthetic Data Cloud empowers dermatology-focused computer vision models by providing meticulously annotated, high-quality synthetic datasets that capture a wide range of skin conditions under diverse imaging conditions. Using SKY ENGINE AI, data scientists can generate realistic training data that accounts for variations in skin tones, lighting, lesion types, and textures, essential for detecting and classifying conditions such as melanoma, acne, eczema, and psoriasis. This synthetic data allows models to recognize subtle, early-stage signs of abnormalities, enhancing diagnostic accuracy and supporting treatment planning. SKY ENGINE AI also enables custom lighting, camera angles, and wavelength-specific simulations, allowing developers to optimize models for teledermatology applications and clinical workflows. With SKY ENGINE AI’s continuous customization options, models can adapt to new diagnostic criteria and emerging skin conditions, making it a vital tool in advancing AI-powered dermatological care.

Computer vision AI for lesion detection in gastroscopy

SKY ENGINE AI’s Synthetic Data Cloud provides a powerful platform for developing and training computer vision models tailored to tumor detection in gastroscopy. By generating highly realistic synthetic datasets that replicate the gastrointestinal tract’s complex anatomy, textures, and lighting conditions, SKY ENGINE AI enables data scientists to train AI models on diverse tumor presentations, including various sizes, shapes, and stages of growth. The platform’s features allow fine control over endoscopic camera positioning, lens properties, and lighting variations, mimicking real-life scenarios and enhancing the AI’s ability to detect subtle tumor indicators. With pixel-perfect annotations, including semantic maps, bounding boxes, and key points, SKY ENGINE AI ensures accurate identification of abnormal tissue patterns, empowering early and precise tumor detection. This approach accelerates model training, reduces reliance on scarce real-world gastroscopy images, and ultimately supports the development of AI solutions that improve diagnostic accuracy and patient outcomes in gastrointestinal oncology.

How to train an AI model for X-ray image analysis

SKY ENGINE AI’s Synthetic Data Cloud is instrumental in developing and validating computer vision AI models for X-ray image analysis, allowing data scientists to create robust, well-annotated datasets that simulate a wide range of anatomical structures and pathologies. With full control over parameters such as X-ray beam angle, intensity, and image resolution, the platform can generate synthetic X-ray images that mimic real-world variability, including patient positioning, bone density, and soft tissue contrast. This flexibility enables the generation of balanced datasets that capture both common and rare conditions, from fractures and joint dislocations to subtle abnormalities like early-stage pneumonia or bone lesions. By training on such richly detailed, physics-based simulations, data scientists can significantly enhance the robustness and diagnostic accuracy of AI models, accelerating the deployment of advanced computer vision tools in radiology for more efficient and accurate X-ray analysis.

Platform features for computer vision AI-assisted medicine

Simulate every detail of sensor configurations

SKY ENGINE AI’s Synthetic Data Cloud provides developers with comprehensive control over all aspects of simulated sensors, from camera placement and focal length to lens distortion and matrix parameters—even down to simulating lens cleanliness. This level of control allows teams to create a digital twin of the sensor, adjusting configurations to match current or experimental setups. By validating sensor configurations virtually, developers can confidently implement real-world setups that align precisely with the model’s object detection capabilities, even testing configurations that don’t yet exist in the physical world.

Multi-modality data generation for visible light, infrared, X-ray, CT, and MRI

SKY ENGINE AI’s Synthetic Data Cloud supports multi-modality data generation, enabling the creation of high-quality, annotated datasets across various imaging types—visible light, infrared, X-ray, CT, and MRI. This versatility allows developers to simulate and train models on data from a wide range of medical imaging modalities, catering to diverse clinical applications such as tissue analysis, fracture detection, and soft tissue differentiation. With physics-based rendering, each modality is precisely tailored to reflect realistic imaging characteristics, including wavelength-specific behavior, noise patterns, and resolution constraints unique to each modality. This comprehensive, modality-specific data ensures that machine learning models can generalize effectively across diagnostic contexts, enhancing accuracy and reliability in multimodal medical AI applications.

Pixel-perfect annotations for accurate AI training

With SKY ENGINE AI, synthetic data is annotated with meticulous, pixel-perfect precision, ensuring high-quality metadata across every dataset. Essential training elements like bounding boxes, semantic maps, key points, and vector annotations are consistently accurate, eliminating the usual variability seen in real-world datasets. This precision in annotations drives significantly more accurate object detection models, as the consistency of metadata allows for more reliable training outcomes and improved model performance.

Realistic depth of field simulation for precision in medical image analysis

Depth of field (DOF) is crucial in medical imaging applications, such as laparoscopy, where clear visualization of specific areas is essential for accurate diagnosis and intervention. SKY ENGINE AI incorporates physically accurate DOF simulation, enabling data scientists to model and train on images that mimic the shallow focus often required in medical procedures. By replicating these imaging characteristics, developers can ensure that machine vision models interpret visuals as they would appear through real-world medical equipment, enhancing precision in tasks like detecting tissue abnormalities or guiding surgical tools.

Other features of SKY ENGINE AI Synthetic Data Cloud for the development of AI-assisted medical image analysis 
  • 3D generative AI and procedural algorithms to create anatomical structures and organs
  • Full control over scene parameters
  • Automatic dataset balancing
  • Parameter-based randomization of a scene
  • Customizable ground truths
  • Synthesis of complex metadata, such as depth and normal maps or semantic masks, 2D/3D key points, and 2D/3D bounding boxes

Summary

SKY ENGINE AI’s Synthetic Data Cloud offers an array of powerful tools and benefits for data scientists and medical professionals working on computer vision AI in healthcare. By generating high-quality synthetic datasets across modalities like X-ray, MRI, and visible light, the platform enables tailored training data for diagnostics, treatment planning, and patient monitoring. With pixel-perfect annotations and meticulous scene customization, SKY ENGINE AI provides richly detailed data that enhances model accuracy, especially for complex use cases like tumor detection, dermatology, and anomaly detection in medical imaging. Its physically-based simulations create realistic imaging conditions—including sensor configuration, depth of field, and multi-modality support—allowing developers to accurately replicate clinical scenarios and improve model robustness across diverse medical applications. SKY ENGINE AI’s adaptability supports continuous model validation and dataset balancing, ensuring AI solutions that are precise, reliable, and ready to address the specific challenges of medical image analysis.

Let us know about your cases and get access to the SKY ENGINE AI Platform or get tailored AI models or synthetic datasets for your AI-powered medical image analysis needs. As we support many more industries than just medicine, a broad range of data customization is available even for specific sensors and environments.